Disease Targets

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Odylia maintains a database of over 300 targeted genes that cause Inherited Retinal Disease (IRD).  We research each target to understand and document each disease’s characteristics along with any science or research that applies to that target.  We record all relevant data such as prevalence, science advancement, models available, current or past clinical trials and score each target as to its viability for gene therapy.  We update the data on a semi-annual release schedule.  Requests for information on a specific gene should sent to info@odylia.org.

Current targets in our database include:

ABCA4

AIPL1

ATXN7

BBS1

BBS4

BEST1

CEP290

CHM

CLRN1

CNGA3

CNGB1

CNGB3

CRB1

GUCY2D

IMPDH1

LRAT

MERTK

MFRP

MYO7A

NYX

PDE6A

PDE6B

PRPH2

RHO

RLBP1

RP1

RP2

RPE65

RPGR

RPGRIP1L

RS1

SPATA7

ABCC6

ABHD12

ACBD5

ACHM1

ADAM9

ADAMTS18

ADGRV1

ADIPOR1

AGBL5

AHI1

AIED

ALMS1

ARL2BP

ARL3

ARL6

ARMS2

ASRGL1

ATF6

BBIP1

BBS10

BBS12

BBS2

BBS5

BBS7

BBS9

BCAMD

C12orf65

C1QTNF5

C2

C21orf2

C2orf71

C3

C8orf37

CA4

CABP4

CACD

CACNA1F

CACNA2D4

CAPN5

CC2D2A

CDH23

CDH3

CDHR1

CEP164

CEP250

CERKL

CFB

CFH

CIB2

CLN3

CLUAP1

CNGA1

CNNM4

COD1

COD2

CODA1

COL11A1

COL2A1

COL9A1

CORD1

CORD17

CORD4

CORD8

CRX

CSPP1

CTNNA1

CYP4V2

DFNB31

DHDDS

DHX38

DMD

DRAM2

DTHD1

EFEMP1

ELOVL4

EMC1

ERCC6

EVR3

EXOSC2

EYS

FAM161A

FBLN5

FHASD

FLVCR1

FSCN2

FZD4

GDF6

GNAT1

GNAT2

GNB3

GNPTG

GPR125

GPR179

GRK1

GRM6

GUCA1A

GUCA1B

HARS

HGSNAT

HK1

HMCN1

HMX1

HTRA1

IDH3B

IFT140

IFT172

IFT27

IMPG1

IMPG2

INPP5E

INVS

IQCB1

ITM2B

JAG1

KCNJ13

KCNV2

KIAA1549

KIF11

KIZ

KLHL7

KSS

LAMA1

LCA5

LHON

LRIT3

LRP5

LZTFL1

MAK

MAPKAPK3

MCDR3

MCDR4

MCDR5

MDDC

MFN2

MFSD8

MIR204

MKKS

MKS1

MRST

MT-ATP6

MT-TH

MT-TL1

MTTP

MT-TP

MT-TS2

MVK

NBAS

NDP

NEK2

NEUROD1

NMNAT1

NPHP1

NPHP3

NPHP4

NR2E3

NR2F1

NRL

OAT

OFD1

OPA1

OPA2

OPA3

OPA4

OPA5

OPA6

OPA8

OPN1LW

OPN1MW

OPN1SW

OR2W3

OTX2

PANK2

PAX2

PCDH15

PCYT1A

PDE6C

PDE6G

PDE6H

PDZD7

PEX1

PEX2

PEX7

PGK1

PHYH

PITPNM3

PLA2G5

PLK4

PNPLA6

POC1B

POMGNT1

PRCD

PRDPRDM13

PROM1

PRPF3

PRPF31

PRPF4

PRPF6

PRPF8

PRPS1

RAB28

RAX2

RB1

RBP3

RBP4

RCBTB1

RCD1

RCD2

RD3

RDH11

RDH12

RDH5

RGR

RGS9

RGS9BP

RIMS1

RNANC

ROM1

RP15

RP16

RP1L1

RP22

RP24

RP29

RP32

RP34

RP5

RP6

RP63

RP8

RP9

RPGRIP1

RTN4IP1

SAG

SDCCAG8

SEMA4A

SLC24A1

SLC25A46

SLC7A14

SNRNP200

SPP2

STGD2

TEAD1

TIMM8A

TIMP3

TLR3

TLR4

TMEM126A

TMEM216

TMEM237

TOPORS

TREX1

TRIM32

TRNT1

TRPM1

TSPAN12

TTC8

TTLL5

TTPA

TUB

TUBGCP4

TUBGCP6

TULP1

UNC119

USH1A

USH1C

USH1E

USH1G

USH1H

USH1K

USH2A

USH2B

VCAN

VMD1

VRD1

WDPCP

WDR19

WFS1

WFS2

ZNF408

ZNF423

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