Odylia maintains a database of over 300 targeted genes that cause Inherited Retinal Disease (IRD). We research each target to understand and document each disease’s characteristics along with any science or research that applies to that target. We record all relevant data such as prevalence, science advancement, models available, current or past clinical trials and score each target as to its viability for gene therapy. We update the data on a semi-annual release schedule. Requests for information on a specific gene should sent to info@odylia.org.
Current targets in our database include:
ABCA4
AIPL1
ATXN7
BBS1
BBS4
BEST1
CEP290
CHM
CLRN1
CNGA3
CNGB1
CNGB3
CRB1
GUCY2D
IMPDH1
LRAT
MERTK
MFRP
MYO7A
NYX
PDE6A
PDE6B
PRPH2
RHO
RLBP1
RP1
RP2
RPE65
RPGR
RPGRIP1L
RS1
SPATA7
ABCC6
ABHD12
ACBD5
ACHM1
ADAM9
ADAMTS18
ADGRV1
ADIPOR1
AGBL5
AHI1
AIED
ALMS1
ARL2BP
ARL3
ARL6
ARMS2
ASRGL1
ATF6
BBIP1
BBS10
BBS12
BBS2
BBS5
BBS7
BBS9
BCAMD
C12orf65
C1QTNF5
C2
C21orf2
C2orf71
C3
C8orf37
CA4
CABP4
CACD
CACNA1F
CACNA2D4
CAPN5
CC2D2A
CDH23
CDH3
CDHR1
CEP164
CEP250
CERKL
CFB
CFH
CIB2
CLN3
CLUAP1
CNGA1
CNNM4
COD1
COD2
CODA1
COL11A1
COL2A1
COL9A1
CORD1
CORD17
CORD4
CORD8
CRX
CSPP1
CTNNA1
CYP4V2
DFNB31
DHDDS
DHX38
DMD
DRAM2
DTHD1
EFEMP1
ELOVL4
EMC1
ERCC6
EVR3
EXOSC2
EYS
FAM161A
FBLN5
FHASD
FLVCR1
FSCN2
FZD4
GDF6
GNAT1
GNAT2
GNB3
GNPTG
GPR125
GPR179
GRK1
GRM6
GUCA1A
GUCA1B
HARS
HGSNAT
HK1
HMCN1
HMX1
HTRA1
IDH3B
IFT140
IFT172
IFT27
IMPG1
IMPG2
INPP5E
INVS
IQCB1
ITM2B
JAG1
KCNJ13
KCNV2
KIAA1549
KIF11
KIZ
KLHL7
KSS
LAMA1
LCA5
LHON
LRIT3
LRP5
LZTFL1
MAK
MAPKAPK3
MCDR3
MCDR4
MCDR5
MDDC
MFN2
MFSD8
MIR204
MKKS
MKS1
MRST
MT-ATP6
MT-TH
MT-TL1
MTTP
MT-TP
MT-TS2
MVK
NBAS
NDP
NEK2
NEUROD1
NMNAT1
NPHP1
NPHP3
NPHP4
NR2E3
NR2F1
NRL
OAT
OFD1
OPA1
OPA2
OPA3
OPA4
OPA5
OPA6
OPA8
OPN1LW
OPN1MW
OPN1SW
OR2W3
OTX2
PANK2
PAX2
PCDH15
PCYT1A
PDE6C
PDE6G
PDE6H
PDZD7
PEX1
PEX2
PEX7
PGK1
PHYH
PITPNM3
PLA2G5
PLK4
PNPLA6
POC1B
POMGNT1
PRCD
PRDPRDM13
PROM1
PRPF3
PRPF31
PRPF4
PRPF6
PRPF8
PRPS1
RAB28
RAX2
RB1
RBP3
RBP4
RCBTB1
RCD1
RCD2
RD3
RDH11
RDH12
RDH5
RGR
RGS9
RGS9BP
RIMS1
RNANC
ROM1
RP15
RP16
RP1L1
RP22
RP24
RP29
RP32
RP34
RP5
RP6
RP63
RP8
RP9
RPGRIP1
RTN4IP1
SAG
SDCCAG8
SEMA4A
SLC24A1
SLC25A46
SLC7A14
SNRNP200
SPP2
STGD2
TEAD1
TIMM8A
TIMP3
TLR3
TLR4
TMEM126A
TMEM216
TMEM237
TOPORS
TREX1
TRIM32
TRNT1
TRPM1
TSPAN12
TTC8
TTLL5
TTPA
TUB
TUBGCP4
TUBGCP6
TULP1
UNC119
USH1A
USH1C
USH1E
USH1G
USH1H
USH1K
USH2A
USH2B
VCAN
VMD1
VRD1
WDPCP
WDR19
WFS1
WFS2
ZNF408
ZNF423